Preimplantation Genetic Testing (PGT) is an advanced laboratory technique used during IVF treatment to assess embryos for specific chromosomal or genetic abnormalities before embryo transfer.
PGT may be recommended in selected fertility cases where there is a medical indication, recurrent pregnancy loss, previous IVF failure, advanced maternal age, known genetic conditions, or concerns related to embryo chromosomal health.
At Umniya Fertility, PGT is incorporated into IVF treatment pathways when clinically appropriate and based on individual fertility history, reproductive goals, and specialist recommendation.
PGT is performed during an IVF or ICSI cycle after embryos develop in the laboratory.
Once embryos reach the blastocyst stage:
Embryos considered suitable may later be selected for frozen embryo transfer depending on embryo development, genetic results, and treatment planning.
PGT does not alter the embryo itself. The testing provides additional genetic information that may help guide embryo selection and reproductive planning.
PGT may be recommended in selected situations including:
Not all IVF patients require PGT. Recommendations are based on fertility investigations, reproductive history, embryo development, and clinical assessment.
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
PGT-A evaluates whether embryos have the correct number of chromosomes.
Chromosomal abnormalities may affect:
PGT-M (Preimplantation Genetic Testing for Monogenic Disorders)
PGT-M screens embryos for specific inherited genetic conditions caused by known gene mutations.
This may be recommended when one or both partners carry a known inherited condition or have a family history of genetic disease.
PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
PGT-SR may be recommended when chromosomal rearrangements such as translocations are identified during fertility or genetic investigations.
PGT is performed as part of an IVF or ICSI treatment cycle.
The process generally includes:
IVF or ICSI Treatment
Eggs are collected and fertilised in the laboratory.
Embryo Development
Embryos are monitored closely as they develop toward the blastocyst stage.
Embryo Biopsy
A small number of cells are removed carefully from the outer layer of the embryo by the embryology team.
Genetic Analysis
The biopsied cells are analysed in a specialised genetics laboratory to assess chromosomal or genetic findings.
Embryo Freezing
Embryos are usually frozen safely using vitrification technology while test results are processed.
Frozen Embryo Transfer
Once results are reviewed, selected embryos may later be transferred during a future treatment cycle.
Depending on the clinical situation, PGT may help:
The role of PGT varies between patients and should be considered within the context of the overall fertility profile and reproductive goals.
Modern embryo biopsy techniques used during PGT are highly specialised and widely used in fertility treatment.
The biopsy removes a small number of cells from the outer portion of the embryo that later forms the placenta, while the inner cell mass that develops into the fetus remains untouched.
Embryos are then frozen using vitrification technology while genetic testing results are processed.
At Umniya, embryo biopsy, embryo freezing, and laboratory monitoring are performed within carefully controlled embryology and genetics protocols.
The process begins with fertility consultation and IVF treatment planning.
Assessment may include:
Throughout treatment, patients are supported by fertility specialists, embryologists, genetics teams, nurses, and care coordinators working together across every stage of the IVF and PGT process.
At Umniya, PGT is performed as part of selected IVF treatment pathways where clinically indicated.
Treatment planning combines:
Recommendations are tailored according to fertility history, reproductive goals, genetic considerations, and embryo development findings.
No. PGT is generally recommended only in selected cases where there is a clinical indication or potential benefit based on fertility history and reproductive assessment.
No. While PGT provides additional information about embryo chromosomal health, pregnancy success still depends on factors such as embryo quality, uterine health, age, and overall reproductive health.
Yes. Embryos are usually frozen after biopsy while genetic testing results are processed before frozen embryo transfer planning.
Modern embryo biopsy techniques are widely used and are generally considered safe when performed by experienced embryology teams.
No. PGT evaluates specific chromosomal or genetic abnormalities depending on the type of testing performed.
IVF is a significant step, and the right preparation makes a real difference. Book a consultation at Umniya Fertility in Abu Dhabi to understand your fertility picture, discuss your options, and begin a treatment plan designed specifically around you. You can also explore the full range of couple fertility treatments available at Umniya.
